Analysis of Liver Histology Several Fish in the Air Kotok River in the Gold Mining Area, Lebong Regency

Fish have habitats that are easily exposed to contamination from the environment such as heavy metal waste which can cause changes in structure and function of body tissues. One type enters river Lebong Regency River is gold mining processing uses mercury cyanide. Heavy metals enter organisms accumulation biomagnification occur bodies aquatic biota fish. There has been no research related fish histology area, so aim this was determine histological condition liver organs several form Hemibagrus nemurus, Rasbora sp, Trichogaster trichopterus, Macrognathus circumcinctus Air Kotok area Regency. The conducted using paraffin method with hematoxylin-eosin staining. Data were analyzed descriptively qualitatively based on liver. results histology, it shows damage includes vacuolization, congestion, pyknosis, dilated sinusoids, melanomacrophages leukocyte infiltration. hepatocytes be used a bio-indicator exposure toxic substances river, one activity mining, threat health survival fish.Keywords: Bengkulu, waste, metal, hepa